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PI3K activity and stemness in hPSCs and breast cancer
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Components
High_depth_iPSCs_H1047R_RNAseq
Files and scripts of relevance to the analysis of the high-depth RNA sequencing data, obtained from human induced pluripotent stem cells with the foll...
M98_iPSCs_E418K_RNAseq
Files and scripts of relevance to the analysis of the RNA sequencing data, obtained from human induced pluripotent stem cells with the following PIK3C...
MEF_H1047R_RNAseq
Files and scripts of relevance to the analysis of the RNA sequencing data, obtained from mouse embryonic fibroblasts with the following PIK3CA genotyp...
GF_replete_iPSCs_H1047R_RPPA_study
Files and scripts of relevance to the analysis of the reverse phase protein array (RPPA) data, obtained from human induced pluripotent stem cells with...
BYL719_iPSCs_H1047R_RPPA_study
Files and scripts of relevance to the analysis of the reverse phase protein array (RPPA) data, obtained from human induced pluripotent stem cells with...
Total_proteomics
This component contains files and scripts of relevance to the analyses of the total proteomics dataset obtained from human induced pluripotent stem ce...
NODAL_experiment
Files and scripts of relevance to the analysis of RT-qPCR data obtained from an experiment with human induced pluripotent stem cells with the followin...
TCGA_BRCA_PIK3CA_NODAL_analysis
Script and files associated with the analysis of TCGA breast invasive carcinoma (BRCA) samples positive for PIK3CA-H1047R. The analysis focused specif...
WGCNA_iPSC_RNAseq_analysis
Weighted Gene Correlation Network Analysis (WGCNA) based on the high-depth RNA sequencing performed on human induced pluripotent stem cells with the f...
METABRIC_TCGA_GSVA_PI3K_stemness_scores
Source data and code underpinning the analyses of inferred PI3K activity and stemness scores in human breast cancers.
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