PI3K activity and stemness in hPSCs and breast cancer

doi:10.17605/OSF.IO/MUERY

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Data and source code are linked to the following publications Madsen, R. R. et al. (2021) ‘NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CA-H1047R homozygosity in pluripotent stem cells’, Disease Models & Mechanisms, 14(3), p. dmm.048298. doi: 10.1242/dmm.048298. Madsen, R. R. et al. (2020) Relationship between stemness and transcriptionally-inferred PI3K activity in human breast cancer. bioRxiv (preprint: https://doi.org/10.1101/2020.07.09.195974). Wherever possible, raw data and source code have been integrated in bespoke RNotebooks with extensive workflow annotations. For issues or any further clarification regarding analyses and data access, please contact Dr Ralitsa Madsen (r.madsen@ucl.ac.uk).

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