Comments To Incorporate into the Paper: I am new to commenting here and can't seem to have the preprint in the same window. The section titled "Randomization and Blinding Procedures" might benefit from adding the topic of systematic procedures or sampling in addition to randomization. For example, when choosing to study the number of neurons in a brain region or how many of those neurons express a certain protein, one will benefit if the experimental procedure is done (1) randomly, (2) systematically and (3) blinded. If we choose completely random sections (not knowing from there they come from) and some sections appear different we have now lost our order and may miss an important finding such as one specific subregion within a brain region expressing a certain protein more or that regions having a higher density of neurons. This is just an example of when it is important to have the procedure random but systematic and blinded. Power Analysis section. I wonder whether it might be useful to point readers and those interested to a source of how to perform a priori power analysis? "Inclusion of Statistically Significant and Nonsignificant Data" section. I know that the Journal of Neuroscience encourages the publication of negative results, but are there others? Should some examples be listed for people to refer to when they have to report negative results? "Registered Reports and Open Practices Badges" section. Since a Stage 1 manuscript can guarantee that the manuscript will be published this could potentially useful when submitting your progress report or prepare your tenure package. However, I wonder how one can cite this 'guarantee'? John Doe et al., guarantee to be published, Journal X? The appendix is great with useful information. Great manuscript overall.