Publishing Transparent and Rigorous Scientific Research

Contributors:
  1. Karen E Chambers
  2. Joshua L Plotkin
  3. David L McArthur
  4. Nidhi Bansal

Date created: | Last Updated:

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Description: Progress in basic and clinical research falters when researchers fail to provide a complete and accurate report of how a study was designed, executed and results analyzed. Publishing rigorous scientific research involves a full description of the methods, materials, procedures and outcomes. Investigators may fail to provide a complete description of how their study was designed and executed, because they may not know how to accurately report that information or mechanisms are not in place to facilitate transparent reporting. Here, we provide an overview of how authors can write manuscripts in a transparent and open manner. We introduce a set of reporting criteria that can be used for publishing, including recommendations on reporting the experimental design and statistical approaches. We also discuss how to accurately visualize results and provide recommendations for peer reviewers to enhance rigor and transparency. Incorporating open transparency practices into research manuscripts will significantly improve the reproducibility of results by independent laboratories.

License: CC0 1.0 Universal

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Comments To Incorporate into the Paper: I am new to commenting here and can't seem to have the preprint in the same window. The section titled "Randomization and Blinding Procedures" might benefit from adding the topic of systematic procedures or sampling in addition to randomization. For example, when choosing to study the number of neurons in a brain region or how many of those neurons express a...

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