Target of replication: *A priori* experimental protocols, materials, and confirmatory analysis plans were peer reviewed, [pre-registered][1], and published by [*eLife*][2].
This component includes all data, analysis scripts, and methods for the replication of the experiment reported in Figures 3B of [Delmore et al., 2011][3]. This experiment assesses the effect of JQ1 on _MYC_ expression in MM.1S cells.
[Figures component][4] contains a visualization of replication results. These figures are the same as can be found in the Replication Study and include Figure 1 displaying _MYC_ expression in JQ1-treated MM.1S cells. These scripts will call data directly from the OSF.
[Statistical Analyses component][5] contains R scripts that were used for the analysis. These scripts will call data directly from the OSF.
[Data component][6] contains data generated from the experimental work and files used in the analysis and generation of figures, which are in .csv format.
[Methods component][7] contains methodology details for this replication attempt which were described in the [Registered Report][8].
[Cell line quality control data][9] includes results confirming the cells lines was free from mycoplasma contamination as well as STR DNA profiling of the cell lines used.
[qRT-PCR quality control data][10] includes RNA concentration and purity of the samples.
[1]: https://osf.io/ng3st/
[2]: https://elifesciences.org/content/4/e07072
[3]: http://www.cell.com/cell/abstract/S0092-8674(11)00943-3?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867411009433%3Fshowall%3Dtrue
[4]: https://osf.io/4fxhn/wiki/home/
[5]: https://osf.io/zcsuh/wiki/home/
[6]: https://osf.io/4ewct/wiki/home/
[7]: https://osf.io/534gy/wiki/home/
[8]: https://elifesciences.org/content/4/e07072
[9]: https://osf.io/r38p3/wiki/home/
[10]: https://osf.io/d2a5w/wiki/home/