Replication Studies  /

Study 19: Replication of Delmore et al., 2011 (Cell)

Contributors:
  1. Fraser Aird
  2. Irawati Kandela
  3. Christine Mantis
Affiliated institutions: Laura and John Arnold Foundation, Center For Open Science

Date created: | Last Updated:

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Category: Project

License: CC-By Attribution 4.0 International

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Replication Study: BET bromodomain inhibition as a therapeutic strategy to target c-Myc Abstract In 2015, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Kandela et al., 2015), that described how we intended to replicate selected experiments from the paper "BET bromodomain inhibition as a therapeutic strategy to target c-Myc" (Delmore et al., 2011). Here ...

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osf.io/7zqxp

Components

  • Evaluation of MYC expression in JQ1-treated MM.1S-luc cells

    Aird, Kandela, Mantis & 5 more

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  • Testing the efficacy of JQ1 treatment in mice harboring bioluminescent MM lesions

    Aird, Kandela, Mantis & 5 more

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  • Meta-analysis


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  • Study 19: Registered Report Additional Materials

    Kandela, Jin, Owen & 6 more

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