This component includes data and analysis scripts for the meta-analyses of the effects from the experiments reported in 3B and Supplementary Figure S6 of [Berger et al. 2012][1] and the replication of this experiment.
**Figure 5. Meta-analyses of each effect.** Effect size and 95% confidence interval are presented for Berger et al., 2012, this replication attempt (RP:CB), and a random effects meta-analysis of the two effects. Sample sizes used in Berger et al., 2012 and this replication attempt are reported under the study name. Hazard Ratio (HR) of tumor free survival in mice bearing tumors from NRAS<sup>G12D</sup> melanocytes expressing PREX2 isoforms or GFP are shown. GFP vs. PREX2<sup>G844D</sup> (meta-analysis *p* = .344), GFP vs. PREX2<sup>Q1430*</sup> (meta-analysis *p* = .376), PREX2<sup>WT</sup> vs. PREX2<sup>G844D</sup> (meta-analysis *p* = .477), PREX2<sup>WT</sup> vs. PREX2<sup>Q1430*</sup>
(meta-analysis *p* = .493).
Access [full size image][2] and [R script][3] used to generate this figure. These scripts will call the [data][4] directly from the OSF.
Access [analysis script][5]. This script will call the data directly from the OSF for the replication data and the [analysis script][6] of the [original data][7].
[1]: http://www.nature.com/nature/journal/v485/n7399/full/nature11071.html
[2]: https://osf.io/t9rd2/
[3]: https://osf.io/5g8dr/
[4]: https://osf.io/82bmx/
[5]: https://osf.io/ar3dv/
[6]: https://osf.io/a9hdg/
[7]: https://osf.io/4b8zu/
