This component includes data and analysis scripts for the meta-analyses of the effects from the experiment reported in Figure 2 and Supplemental Figure 9A of [Sugahara et al. 2010][1] and the [replication][2] of these experiments.
**Figure 5. Meta-analyses of each effect.** Effect size and 95% confidence interval are presented for Sugahara et al., 2010, this replication attempt (RP:CB), and a random effects meta-analysis to combine the two effects. Sample sizes used in Sugahara et al., 2010 and this replication attempt are reported under the study name. (**A**) Dox accumulation in tumor tissue of mice treated with 10 mg/kg DOX alone or 10 mg/kg DOX and 4 µmol/kg iRGD (_p_ = .237). (**B**) Tumor weight of mice treated with 1 mg/kg DOX or 1 mg/kg DOX and 4 µmol/kg iRGD _p_ = .195). (**C**) Body weight shift of mice treated with PBS, 1 mg/kg DOX and PBS, or 1 mg/kg DOX and 4 µmol/kg iRGD (_p_ = .229). (**D**) TUNEL staining from mice treated with 1 mg/kg DOX or 1 mg/kg DOX and 4 µmol/kg iRGD (_p_ = .211).
Access [full size image][3] and [R script][4] used to generate this figure. These scripts will call the [data][5] directly from the OSF.
Access [analysis script][6]. This script will call the data directly from the OSF for the replication data.
[1]: http://science.sciencemag.org/content/328/5981/1031
[2]: https://osf.io/xu1g2/
[3]: https://osf.io/mkcpd/
[4]: https://osf.io/4ynre/
[5]: https://osf.io/6gky9/
[6]: https://osf.io/3sj2u/