The specific objectives of this scoping review will answer the following questions:
1. Map the explicit knowledge content from the SEP literature, including extensive prior to glean lessons learned to a set of global health domains
2. Map the explicit knowledge the SEP key conveners, namely PAHO and WHO and specific governing committees and designated entities that they convened.
We included studies that cover any aspect of the Smallpox Eradication Program that relates to how it has worked and what can be learned from it. We included articles on the gloabl experience as well as articles from the PAHO region and all countries in the WHO region of the Americas. We searched PubMed, EMBASE, and Scopus for publications from the period January 1, 1950 to May 7, 2018.