Early detection of psychosis is crucial for positive clinical outcomes. To
detect (or even delay) first symptoms, it is important to be able to
identify pre existing, sub-clinical, individual risk factors. The purpose
of the current study is to better understand and characterize the
behavioral and neurophysiological patterns that might point to a vulnerable
structure. Clinical experience, as well as scientific studies, demonstrate
that psychotic disorders are characterized by recognizable linguistic
features (Bazan, 2012), as well as by difficulties in cognitive
inhibition (Schneider
et al., 1982). Therefore, we used a linguistic inhibition task to compare
and contrast participants with low psychotic traits and participants with
high psychotic traits, measured by the Schizotypal Personality Questionnaire
(Raine, 1991). Fifty-one non-clinical participants took part in a modified
version of the ThinkNoThink paradigm (Anderson & Green, 2001). Behavioral
(number of correctly recalled word pairs after an inhibition task) and
neurophysiological (EEG) response patterns will be analyzed. We expect to
observe that participants with high psychotic traits will show better
recall (a sign of less efficient inhibition) and weaker alpha brain wave
synchronization (a less efficient neurophysiological mechanism of active
inhibition), compared to participants with low psychotic traits. These
results can serve as a basis for the future development of a non-invasive,
objective, and easy to administer linguistic tool that can be used in
clinical practice to detect psychotic vulnerability.