Main content
Strength of evidence for the efficacy of oncological drugs: A comparison of endpoints, approval pathways, and types of treatment
Date created: | Last Updated:
: DOI | ARK
Creating DOI. Please wait...
Category: Project
Description: We aim to demonstrate the utility of adopting a Bayesian framework to quantify evidential strength and uncertainty for statistical evaluations of benefits of novel cancer drugs at the time of approval. Reanalysing data from the CEIT-Cancer project, we aim to (1) describe evidential strength for clinical trials of drug and biologic products approved for the treatment of cancer in the last two decades; (2) contrast evidential standards between endpoints, accelerated vs. non-accelerated approval, lines of treatment, and type of cancer to describe potential differences in evidential strength.
Start managing your projects on the OSF today.
Free and easy to use, the Open Science Framework supports the entire research lifecycle: planning, execution, reporting, archiving, and discovery.