>Open Access: The Effect of Neurorehabilitation on Multiple Sclerosis – Unlocking the Resting-State fMRI Data ---------- This dataset contains the resting-state fMRI data of 60 people with Multiple Sclerosis, acquired before and after two months of neuroproprioceptive "facilitation and inhibition" treatment. **If you use this dataset in your research, please make sure that you reference the related [data paper][1] with detailed description of the data: *Bučková, Barbora, et al. "Open Access: The Effect of Neurorehabilitation on Multiple Sclerosis—Unlocking the Resting-State fMRI Data." Frontiers in neuroscience 15 (2021).*** ---------- The data contain the following information: **clinical.csv** Clinical information about subjects. - **ID**: subject identifier. - **SEX**: "M" or "F" identifying males and females. - **MS_TYPE**: type of multiple sclerosis either "remitting_relapsing", "primary_progressive" or "secondary progressive". - **AGE**: age at the time of the study. - **EDSS**: Expanded Disability Status Scale at the time of the study. - **DATASET**: whether the subject was a part of the pilot or the consecutive project (is relevant because of the slight change in the fMRI acquisition parameters). - **DIAG_YEARS**: number of years since diagnosis. - **BMI**: BMI at the time of the study. - **THERAPY**: type of rehabilitation (see [Prochazkova et al 2020][2]). - **outliers_V1**: the absolute number of volumes flagged as outliers participant's first visit ([step 3][3] of the CONN pipeline). - **outliers_V2**: the absolute number of volumes flagged as outliers participant's second visit ([step 3][3] of the CONN pipeline). ---------- The **nifti** directory contains [CONN][4] preprocessed fMRI time-series. ---------- The **quality measures** contains files with the appropriate displacement measures for each subject and visit. - **DVARS.csv** - **FD.csv** ---------- The **AAL_timeseries** contains functional connectivity timeseries as **.csv** for each subject and visit (one row equals activity in one region). ---------- The **FC** contains functional connectivity matrices as **.csv** for each subject and visit, as well as the file **AAL_labels.csv** with labels of AAL atlas regions. ---------- For more work from the **COBRA** group, please visit our [website][5] [1]: https://www.frontiersin.org/articles/10.3389/fnins.2021.662784/full [2]: https://journals.lww.com/intjrehabilres/Abstract/2015/03000/Motor_programme_activating_therapy_influences.6.aspx [3]: https://web.conn-toolbox.org/home [4]: https://web.conn-toolbox.org/fmri-methods/preprocessing-pipeline [5]: http://cobra.cs.cas.cz/