**Figure 1. Cellular I-BET151 dose response curves in MLL-fusion leukaemia and non-MLL-fusion leukaemia cell lines.** Cell viability assays were performed for a MLL-fusion leukaemia cell line (MV4;11) and a non-MLL-fusion leukaemia cell line (K-562) with the I-BET151 inhibitor. Curves and absolute IC<sub>50</sub> values were determined for each biological repeat. (**A**) Dose response curves for each biological repeat [n=5] for the MV4;11 cell line. Percent cell viability is relative to DMSO treated cells. I-BET151 doses range from 1 pM to 1 mM. Exploratory one-sample _t_-test of IC<sub>50</sub> values compared to a constant of 100 µM; _t_(4) = 20.63, _p_ = 3.26x10<sup>-5</sup>; Cohen’s _d_ = 9.23, 95% CI [3.13, 15.45].
Access the [analysis script][1] for the statistical tests related to this figure. The script will call the [data][2] directly from the OSF.
[1]: https://osf.io/uy46p/
[2]: https://osf.io/vgaz7/
