Sagittal craniosynostosis (SCS) is the most common type of premature perinatal cranial suture fusion and results in an abnormal elongated skull shape that requires early surgical intervention in to correct. Objective and reproducible shape measurements are needed to study the effect of the timing and surgical technique on head shape maintenance in craniosynostosis patients.
![Sample meshes generated from the growth models for normative and sagittal craniosynostosis cohorts.][1]
This project aims to develop statistical models of infant skull growth for 0 to 6 months of age in both normative and non-syndromic SCS subjects. Using 81 pre-operative CT scans of isolated non-syndromic SCS patients and 117 CT scans for normative cohort, we produced two population-level templates. Then we modeled the cranial growth with the help of 38 manually annotated anatomical landmarks.
[1]: https://files.osf.io/v1/resources/kft8y/providers/osfstorage/5d0a65e211bd080018a01dca?mode=render