Assessing the Relationship between Low-Calorie Sweetener Use and Quality of Life Measures in Adults with Type 1 Diabetes
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Description: Less than third of the adults with type 1 diabetes (T1D) in US achieve American Diabetes Association (ADA) goals for HbA1c; i.e. HbA1c <7% for adults without significant comorbidities. Despite advances in diabetes technologies and therapeutics in recent years, postprandial hyperglycemia has been a major contributor of elevated HbA1c .Amount of carbohydrate intake negatively affect the postprandial glycemia and uncontrolled diabetes have a negative impact of quality of life (QOL) and overall well-being of patients with T1D. QOL is an important factor in diabetes management and has a positive impact on diabetes outcomes. In parallel, optimal glycemic control which may be achieved with decreased carbohydrate intake has been shown to improve QOL in patients with diabetes. For some people with diabetes who are accustomed to regularly consuming sugar-sweetened products, low-calorie sweeteners (LCS) may be an acceptable substitute for nutritive sweeteners. Reducing carbohydrate intake and substituting with LCS may have some role in improving postprandial glycemic control and related improvement of QOL in patients with diabetes. However, role of LCS on QOL has not been studied in adults with T1D therefore, we propose this study to assess the relationship between LCS and QOL measures in adults with T1D.