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This umbrella review aims to summarize and synthesize findings from reviews on involving young people in health research, consolidate the challenges experienced in youth involvement and the recommendations to mitigate these challenges, identify the best practices in involving young people in health research, and identify gaps and methodological weaknesses in the extant literature. PROSPERO record https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021287467
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