Safety Seeking Behavior Mediated by Cholecystokinin-Expressing Neurons in the Lateral/ventrolateral Periaqueductal Gray

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Abstract The periaqueductal gray (PAG) is implicated in numerous defensive responses such as analgesia, freezing and avoidance. However, which subdivisions and cell types within the PAG are responsible for these behaviors is not completely understood. Cholecystokinin-expressing neurons (CCK+) robustly populate the lateral/ventrolateral PAG, yet they remain largely uncharacterized. Our early fiber ...

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