Depression and Acute Stress Impair Selectivity for Learning Important Information

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Early life stress (ELS) and psychological stress have been shown to interfere with memory and decision-making. Research in rodents suggests these impairments stem from disruption of the brain regions responsible for reward and value calculations. Major depression is associated with impairment of one of these regions (nucleus accumbens) in humans undergoing neuroimaging. However, there is a diverse...

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