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**DESCRIPTION** These files contain the data and the research script about the effectiveness of the 38% silver diamine fluoride (SDF, SDI Riva Star) and Tiefenfluorid (TF, Humanchemie GmbH), using two different application protocols in children ≤71 months of age with early childhood caries, with a focus on patient-centred outcomes including major complications (pain, abscess, extraction) and minor complications (lesion progression). **KEYWORDS** silver diamine fluoride, non-invasive caries management, early childhood caries, randomised controlled trial, patient-centered outcomes research **CONTACT** Sergio Uribe, sergio.uribe@rsu.lv **CREATION DATE** (yyyy-mm-dd) 2023-02-25 **GRANT/FUNDING ASSOCIATED** This research was financed by Postdoc Latvia, 1.1.1.2/VIAA/3/19/543, contract no 9.-14.5/27. S.E.U. acknowledges financial support from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 857287. **FILES** 01_readme.txt 02_codebook.html 03_dataset.csv Contains the original raw data 04_r_exploratory.Rmd Contains the descriptive and exploratory analysis script in rmarkdown format to be read using Rstudio. 05_r_regression.Rmd Contains the regression modelling in rmarkdown format to be read using Rstudio. **PREREQUISITES TO REPLICATE THE ANALYSIS** To recreate the analysis you need to 1. to install the pacman package in R 2. Create a folder called "figures" where the figures will be saved. 3. Create a folder called "data" and store there a copy of the dataset 4. Run the R script
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