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Description: Abstract A model of personality pathology including both general and specific components distinguishes severity of personality dysfunction from the characteristic style of its expression. Whether and how general and specific features of personality pathology relate to momentary dynamics of affect and interpersonal behavior remain open questions. We explored these questions in a student sample (N=294) and pre-registered replication in a community sample (N=311). Ecological momentary assessment was used to measure affect, dominance, and warmth of self and other during interpersonal interactions. We examined one’s average affect and behavior and of one’s perception of the other’s behavior, and variability in these constructs. Associations between interpersonal patterns and personality pathology were estimated using multilevel structural equation modeling in each sample separately and in the pooled dataset. Results support the potential clinical impact of empirical models by demonstrating the structural independence of general and specific features, along with relationships to theoretically meaningful interpersonal behavior.