This proof-of-concept study will determine whether a standard laboratory protocol used to induce a cortisol response will continue to work in an online data collection platform. If so, the study will also be able to examine whether the stress they and their family are under during this pandemic and their tendency toward anxiety, are related to the likelihood or magnitude of a cortisol response. The Trier Social Stress Test is the gold standard for activating the stress-responsive hypothalamic-pituitary-adrenocortical (HPA) axis, a core stress system of the body (Dickerson & Kemeny, 2004). Originally developed for use with adults (Kirschbaum, Pirke & Hellhammer, 1993), it has been adapted for use with children and adolescents (Kudielka et al., 2004). We have assessed hundreds of children and adolescents using this task (e.g., Doom et al., 2015; Hostinar, Gunnar & Johnson, 2015). The TSST is a standardized protocol in which the participant delivers a 5 minute speech in front of two judges and then does difficult mental arithmetic designed to result in errors. They are told they are being filmed and that their video will be shown to others who will score their behavior. The task creates a strong sense of being socially evaluated which activates the stress system. During this time of pandemic the TSST, which is typically conducted live with the participant and parent coming to the research laboratory, cannot be completed. However, it might be possible to conduct the protocol effectively using the ZOOM platform. This is what we are proposing to determine. Can the protocol be adapted to an online platform and using this platform can we obtain a significant stress response? If it can, then we can continue to use the online platform during periods when the opportunity for “live” testing may be unreliable because COVID19 flare-ups may result in renewed periods of “shelter in place”. It would also be a boon to the research on children with relatively rare conditions where a national sample is needed. Such studies could be run from one central place with only the need to adjust for time zone differences.