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Target of replication: *A priori* experimental protocols, materials, and confirmatory analysis plans were peer reviewed, [pre-registered][1], and published by [*eLife*][2]. This component includes all primary data, analysis scripts, and QC data for the replication of the experiment reported in Figure 3B and S6B-C of [Berger et al., 2012][3]. This experiment was performed to assess the impact of PREX2 expression on tumor growth and tumor free survival in mice injected with NRAS<sup>G12D</sup> melanocytes stabily expressing GFP, PREX2<sup>WT</sup>, PREX2<sup>G844D</sup>, or PREX2<sup>Q1430*</sup>. ## Contents [Figures Component][4] contains a visualization of replication results. These figures are the same as can be found in the Replication Study and include Figures 3 and 4. [Statistical Analyses Component][5] contains R scripts that were used for the analysis. [Data Component][6] contains data generated from the experimental work and files used in the analysis and generation of figures, which are in .csv format. [Methods Component][7] contains methodology details for this replication attempt which were described in the [Registered Report][2]. [Cell line quality control data][8] includes results confirming the cell lines were free of mycoplasma contamination as well as STR DNA profiling of the cell lines used. [1]: [2]: [3]: [4]: [5]: [6]: [7]: [8]:
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