## Description of contents ## This repository contains data and code for the manuscript *Applying genome-wide CRISPR to identify known and novel genes and pathways that modulate formaldehyde toxicity* by Yun Zhao et al. available at [https://doi.org/10.1016/j.chemosphere.2020.128701][1]. - **Raw data:** Next generation sequencing count data for various CRISPR probes after 8 or 20 days of exposure to 40, 100, or 150 μM formaldehyde - **edgeR results:** Test statistics produced by using BioConductor's *edgeR* package to detect significant differences between control and exposed cell populations - **Code:** Example code to produce results in the **edgeR results** folder from the count data in the **Raw data** folder Select CRISPR screen datasets are also available on BioGRID ORCS: - [8 days 100 µM Formaldehyde][2] - [8 days 150 µM Formaldehyde][3] [1]: https://doi.org/10.1016/j.chemosphere.2020.128701 [2]: https://orcs.thebiogrid.org/Screen/1396 [3]: https://orcs.thebiogrid.org/Screen/1397