Effects of enhanced dopaminergic neurotransmission on working memory training efficiency in the healthy elderly

doi:10.17605/OSF.IO/AAM9U

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### **REBOOT-II :** *Effects of enhanced dopaminergic neurotransmission on working memory training efficiency in the healthy elderly* #### **Aim** Administration of the dopamine precursor L-dopa will allow restoring learning abilities by compensating age-related decline in dopaminergic neurotransmission involved in neurobiological and cognitive plasticity. #### **Endpoints** * ##### **Primary :** * Fluid Intelligence (Gf): * Spatial Intelligence (BETA-III, WASI-II, Raven's matrices) * Verbal Intelligence (BIS analogies, Syllogisms, ETS Kit inference) * ##### **Secondary :** * Updating and rule-switching * Episodic Memory * Creativity * Structural and Functional connectivity ___ #### **Links :** [Reboot-II: training and testing batteries (Trello Board)][1] [1]: https://trello.com/b/mqOdaryz/reboot-games-v-2-0

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