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**ABSTRACT** *Introduction:* Medication errors represent a concern for healthcare organizations due to their negative consequences. In the nursing context, these errors represent a threat to the quality of care and patient safety. Many factors have been identified as potential for these errors in intensive care units. *Aim:* To identify interventions/strategies to minimize the occurrence of medication errors by nurses. *Methods:* A scoping review will be developed, considering the Joanna Briggs Institute (JBI) methodology. A search will be conducted in the EbscoHost (CINAHL Complete and MEDLINE) and PubMed databases. Data analysis, extraction and synthesis will be carried out by reviewers independently. *Results:* This review will allow the mapping of which interventions are more specific to minimize medication error, by nurses in intensive care, and recognise which factors influence this type of error to mitigate practices that may lead to error. *Conclusion:* This protocol acts as the framework for a scoping review in the strategy to map the interventions and which factors contribute to the medication error by intensive care nurses. **RESEARCH QUESTION** • Which interventions prevent medication errors by nurses in intensive care units? **Secondary questions** • Which factors predispose to medication errors among nurses in intensive care units? • Which consequences and outcomes result from the occurrence of medication errors by nurses in intensive care units? **INCLUSION CRITERIA** **Participants/population** This review will consider studies focusing on nurses. All nurses (general care, specialist/parental, and advanced practice nurses) will be included, regardless of length of professional practice or level of training. Studies whose participants are doctors, pharmacists, nursing assistants, or nursing students will not be included, as will studies that refer to pediatric and neonatal intensive care units. **Concept** Interventions and strategies to prevent medication error by nurses, as well as associated factors and consequences of medication error in this professional group. **Context** *Inclusion:* adult intensive care units of any type (multipurpose intensive care, coronary intensive care, neurocritical intensive care, respiratory intensive care, among others). *Exclusion:* intermediate care units or pediatric and neonatal intensive care units. **Types of studies** This review will include primary, quantitative, qualitative, and mixed-methods peer-reviewed studies that meet the inclusion criteria. The review will also include reviews of quantitative, qualitative, or mixed-methods studies, provided they are eligible as described above. In terms of quantitative primary studies, experimental, quasi-experimental, transversal, cohort, and case-control designs will be admitted. In the qualitative methodology paradigm, studies using the phenomenological method, grounded theory, and action research, among others, will be included. Reports or technical documents may also be included, as long as they are issued by qualified bodies, such as state bodies, professional organizations, or scientific societies. Opinion texts and articles, as well as letters to the editor and editorials, will be excluded.
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