This OSF page summarizes some of the data and scripts used for the study by Daria EA Jensen, Klaus P Ebmeier, Sana Suri, Matthew FS Rushworth, Miriam C Klein-Flügge published in Nature Communications in 2024 entitled: "Nuclei-specific hypothalamus networks predict a dimensional marker of stress in humans" Link: https://www.nature.com/articles/s41467-024-46275-y DOI: https://doi.org/10.1038/s41467-024-46275-y (1) hypoNuclei/: There is a folder which contains binary masks of the hypothalamus nuclei generated in the study - please refer to the Methods section for more detail. (2)hypoMasks/: There is a second folder which contains masks of the whole hypothalamus at different resolutions. (3) rois/: There is a third folder which contains binary masks of the ROIs used in the study - again, please see the Methods section of the paper for how they were extracted. (4) scripts/: There is a folder which contains the essential scripts for the analysis in the study. For HCP users, this code should be sufficient to replicate figures, analyses and results presented in the manuscript and supplementary information. Non-HCP users first need to apply for access to the restricted and unrestricted HCP data (https://humanconnectome.org/). The data used in this manuscript was the minimally processed data, some of the questionnaire data (both restricted and unrestricted) as well as the physiological monitoring data (cardiac and respiratory). Once access to these data has been obtained separately, the scripts made available here will allow the researcher to replicate the analyses and reproduce the figures generated in the manuscript. See 'README_Scripts.pdf' for detailed explanation of the scripts provided explanation. (5) SourceData_figure/: Finally, there is a folder which contains the data source files to reproduce the figures in the manuscript and supplementary. See 'README_SourceData.txt' for details on files. Feel free to contact me with any questions! Daria