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Description: Preamble – This study protocol is one among the 16 study protocols of reviews conducted by the working group 3 (WG3) of the COST Action CA20128 - Promoting Innovation of Fermented Foods (PIMENTO). These reviews summarize the evidence for a set of 16 functional properties of fermented foods. WG3 reviews follow the guidance of the European Food Safety Authority (EFSA) “Scientific and technical guidance for the preparation and presentation of a health claim application” (EFSA Panel on Dietetic Products, 2021b). This guidance is composed of three major parts: (i) a systematic review of human studies; (ii) a non-systematic reviewing of the characteristics of the investigated fermented foods; (iii) a non-systematic reviewing of evidence supporting the functional properties of the investigated fermented foods, in particular the mechanism of action and the bioaccessibility and bioavailability of the active compounds. In addition, safety aspects will also be considered in the reviews. The systematic reviewing of the human studies is conducted based on the guidance by Muka et al. (Muka et al., 2020). The PROSPERO study protocol is used as basis to structure the reviewing process of the human studies. It is also adapted to the needs of the WG3 reviews to include the non-systematic parts of the reviews described above to create this generic PIMENTO Study Protocol (PIMENTO-SP). Each of the sections below contains a generic methodology valid for all reviews. The PIMENTO-SP, however, allows for the introduction of review-specific information and methodology. The study protocols of each of the 16 WG3 reviews are deposited in Open Science Framework Registries (OSF) (https://osf.io/registries) using the Open-Ended-Registration modus (Bakker et al., 2020). The narrative summary of the review also deposited in OSF is a copy-paste of the paragraph describing the review in the PIMENTO position paper by Todorovic et al. to which this study protocol is linked. This study protocol (PIMENTO-SP-E6) describes the workflow aimed at reviewing text. The review based on this study protocol uses the EFSA guidance [Guidance on the scientific requirements for health claims related to bone, joints, skin, and oral health”, the “Scientific and technical guidance for the preparation and presentation of a health claim application, and the “General scientific guidance for stakeholders on health claim applications”].