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Description: Reference: Registered Report Protocol: Fekete, A., Maidhof, R. M., Specker, E., Nater, U. M., & Leder, H. (2022). Does art reduce pain and stress? A registered report protocol of investigating autonomic and endocrine markers of music, visual art, and multimodal aesthetic experience. PLOS ONE, 17(4), e0266545. https://doi.org/10.1371/journal.pone.0266545 Abstract While the pain- and stress-reducing effects of music are well investigated, effects of visual art and the combination of both modalities (music and visual art) are much less explored. We tested the (1) pain- and (2) stress-reducing effects of a multimodal (music + visual art) aesthetic experience—expecting stronger effects than single modal aesthetic experiences (music or visual art)—and, in an exploratory manner, (3) investigated underlying mechanisms of aesthetic experience and (4) individual differences. In a repeated-measures design (music, visual art, multimodal aesthetic experience, control), 42 female participants submitted their self-selected “movingly beautiful” visual artworks and music pieces to the lab, where pain and stress were induced by a cold pressor test. Pain (global pain perception, pain intensity, pain affect, pain tolerance) and stress responses (subjective reports, autonomic [electrocardiography, electrodermal activity, salivary alpha-amylase] and endocrine activity [salivary cortisol]) were measured. Individual differences of the experience, trait empathy and absorption were investigated. Exposure to multimodal art resulted in longer pain tolerance than single modality of visual art, but no difference was found for music. Other measures of pain intensity, stress intensity, and pain affect did not differ across the conditions. Regarding the mechanisms, exposure to all types of art distracted participants’ attention from pain, prompted mind wandering, and elicited greater enjoyment than the control condition . Physiological measures of electrocardiography and electrodermal activity validated our design: participants were more stressed during the cold pressor test, but no differences were observed across the four conditions. Also, no differences were found regarding cortisol and alpha-amylase. Regarding individual differences, higher trait absorption was associated with longer pain tolerance in the multimodal condition and with lower pain intensity in the music-only condition, compared to the other conditions. In conclusion, exposure to art can influence pain; however, the underlying mechanisms require further research.

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