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<p>This component includes data and analysis scripts for the meta-analyses of the effects from the experiment reported in Figure 2 and Supplemental Figure 9A of <a href="http://science.sciencemag.org/content/328/5981/1031" rel="nofollow">Sugahara et al. 2010</a> and the <a href="https://osf.io/xu1g2/" rel="nofollow">replication</a> of these experiments.</p> <p><strong>Figure 5. Meta-analyses of each effect.</strong> Effect size and 95% confidence interval are presented for Sugahara et al., 2010, this replication attempt (RP:CB), and a random effects meta-analysis to combine the two effects. Sample sizes used in Sugahara et al., 2010 and this replication attempt are reported under the study name. (<strong>A</strong>) Dox accumulation in tumor tissue of mice treated with 10 mg/kg DOX alone or 10 mg/kg DOX and 4 µmol/kg iRGD (<em>p</em> = .237). (<strong>B</strong>) Tumor weight of mice treated with 1 mg/kg DOX or 1 mg/kg DOX and 4 µmol/kg iRGD <em>p</em> = .195). (<strong>C</strong>) Body weight shift of mice treated with PBS, 1 mg/kg DOX and PBS, or 1 mg/kg DOX and 4 µmol/kg iRGD (<em>p</em> = .229). (<strong>D</strong>) TUNEL staining from mice treated with 1 mg/kg DOX or 1 mg/kg DOX and 4 µmol/kg iRGD (<em>p</em> = .211).</p> <p>Access <a href="https://osf.io/mkcpd/" rel="nofollow">full size image</a> and <a href="https://osf.io/4ynre/" rel="nofollow">R script</a> used to generate this figure. These scripts will call the <a href="https://osf.io/6gky9/" rel="nofollow">data</a> directly from the OSF.</p> <p>Access <a href="https://osf.io/3sj2u/" rel="nofollow">analysis script</a>. This script will call the data directly from the OSF for the replication data.</p>
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