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Category: Project

Description: Are neural responses to drug cues associated with relapse in patients with a stimulant use disorder? In this cohort study of 76 participants, patients showed greater mesolimbic activity to drug cues than did controls, but nucleus accumbens responses to drug cues were specifically associated with the later occurrence and timing of relapse in patients to a greater extent than were conventional self-report and clinical measures. Neural responses to stimulant cues may help identify patients at greatest risk for relapse, which could improve targeting of interventions.