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<h3>Overview</h3> <p>The <strong>dual-hub account</strong> posits that the neural organization of semantic knowledge is segregated by the type of semantic relation with <em>anterior temporal lobe</em> (<strong>ATL</strong>) specialized for <em>taxonomic relations</em> and <em>inferior parietal lobule</em> (<strong>IPL</strong>) specialized for <em>thematic relations</em>. </p> <p>This study critically examined this account by recording intracranial EEG from an array of depth electrodes within ATL, IPL, and two regions within the semantic control network, inferior frontal gyrus (IFG) and posterior middle temporal gyrus (pMTG), while 17 participants with refractory epilepsy completed a semantic relatedness judgment task. We observed a significant difference between relation types in ATL and IPL approximately 600-800ms after trial presentation, and no significant differences in IFG or pMTG. Within this time window, alpha and theta suppression indexing cognitive effort and memory retrieval was observed in ATL for taxonomic trials and in IPL for thematic trials. These results suggest taxonomic specialization in ATL and thematic specialization in IPL, consistent with the dual-hub account of semantic cognition.</p> <hr> <p><img alt="graphical abstract" src="https://files.osf.io/v1/resources/xtfah/providers/osfstorage/5fb5184f5502ac023f8c8ee6?mode=render"></p> <hr> <p>This wiki outlines the different components of the project and is divided into the following sections:</p> <ol> <li><strong><a href="https://osf.io/xtfah/wiki/Data/" rel="nofollow">Data</a></strong> - an overview of the publicly available data including supplemental materials not included in the manuscript.</li> <li><strong><a href="https://osf.io/xtfah/wiki/Preprocessing%20Pipeline/" rel="nofollow">Preprocessing Pipeline</a></strong> - details how the icEEG data were preprocessed.</li> <li><strong><a href="https://osf.io/xtfah/wiki/Statistical%20Analysis/" rel="nofollow">Statistical Analysis</a></strong> - information on how the data were analyzed.</li> <li><strong><a href="https://osf.io/xtfah/wiki/Task%20Information/" rel="nofollow">Task Information</a></strong> - additional detail on the task stimuli.</li> </ol> <hr>
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