Region-specific elevations of glutamate + glutamine correlate with the sensory symptoms of autism spectrum disorders

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Individuals on the autism spectrum are often reported as being hyper- and/or hypo-reactive to sensory input. These sensory disturbances were one of the key observations that led to the development of the altered excitation-inhibition (E-I) model of autism, which posits that an increase ratio of excitatory to inhibitory signaling may explain certain phenotypical expressions of autism spectrum disor...

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