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Early detection of psychosis is crucial for positive clinical outcomes. To detect (or even delay) first symptoms, it is important to be able to identify pre existing, sub-clinical, individual risk factors. The purpose of the current study is to better understand and characterize the behavioral and neurophysiological patterns that might point to a vulnerable structure. Clinical experience, as well as scientific studies, demonstrate that psychotic disorders are characterized by recognizable linguistic features (Bazan, 2012), as well as by difficulties in cognitive inhibition (Schneider et al., 1982). Therefore, we used a linguistic inhibition task to compare and contrast participants with low psychotic traits and participants with high psychotic traits, measured by the Schizotypal Personality Questionnaire (Raine, 1991). Fifty-one non-clinical participants took part in a modified version of the ThinkNoThink paradigm (Anderson & Green, 2001). Behavioral (number of correctly recalled word pairs after an inhibition task) and neurophysiological (EEG) response patterns will be analyzed. We expect to observe that participants with high psychotic traits will show better recall (a sign of less efficient inhibition) and weaker alpha brain wave synchronization (a less efficient neurophysiological mechanism of active inhibition), compared to participants with low psychotic traits. These results can serve as a basis for the future development of a non-invasive, objective, and easy to administer linguistic tool that can be used in clinical practice to detect psychotic vulnerability.
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