Objective: to map concepts and findings about the quality of life of children, adolescents, and young adults with type 1 neurofibromatosis. Method: scope review protocol based on the Joanna Briggs Institute guidelines and registered on the Open Science Framework platform. Data search will be performed on PubMed/MEDLINE, EMBASE, Web of Science, CINAHL, Open Gray and Google Scholar platforms. Manuscripts found will be organized through the EndNote manager to identify and exclude duplicates. Subsequently, the articles and other materials will be transferred to the Rayyan software, for screening and selection of eligible studies by two independent researchers, this entire process being described in a flowchart adapted from the PRISMA-ScR Checklist. Data extracted from eligible manuscripts will be presented in tables, charts and flowcharts, as appropriate. The data will be discussed and interrelated, with the purpose of identifying potentialities and limitations regarding the research theme.