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Description: Pre-registration of Study Design and Analysis Plan: https://osf.io/m8jmp/register/564d31db8c5e4a7c9694b2c0 PsyArXiv Preprint Manuscript: https://osf.io/z2kvh/ The objective of the current study is to examine norepinephrine alpha1 (NE-α1) receptor involvement in reactivity to unpredictable stressors in humans, by using the NPU stress task in conjunction with an alpha1-blocker, prazosin.

License: CC-By Attribution 4.0 International

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Noradrenergic alpha1 mechanisms of stress reactivity in humans | Registered: 2016-11-07 23:02 UTC

The objective of the current study is to examine norepinephrine alpha1 (NE-α1) receptor involvement in reactivity to unpredictable stressors in humans...

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Acute prazosin administration does not reduce stressor reactivity in healthy adults

Kaye, Fronk, Zgierska & 3 more
Background: Norepinephrine plays a critical role in the stress response. Clarifying the psychopharmacological effects of norepinephrine manipulation o...

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