Mindfulness appears to have extensive benefits in areas as diverse as cognitive performance, self-regulation, emotion, mental and physical health, and prosocial behavior. This research sought to test the efficacy of a brief, frequent mindfulness intervention in undergraduate classes for which mindfulness was not the primary topic of study. I implemented this training in four psychology classes ranging in size from 31 to 440 students. Each week, students participated in 5 minutes of guided mindfulness meditation and/or a few minutes of low-impact yoga. In Study 1, students reported that they enjoyed the experience, it increased their engagement in the class, decreased their anxiety, had a positive influence on their life outside of class, and they were interested in participating in mindfulness activities outside of class. In Study 2, students who participated more fully in mindfulness were more likely to report that the activities increased enjoyment of and engagement with class, feeling connected with class, and coping skills, and decreased their anxiety about class, social situations, and in other areas of life. The vast majority of students benefit from this relatively easy and accessible intervention.