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The uncinate fasciculus in individuals with and at risk for bipolar disorder: A meta-analysis
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Description: The present meta-analysis aims to examine whether altered fractional anisotropy of the left and right uncinate fasciculus (UF) represent an endophenotype of bipolar disorder (BD). Second, we aim to determine whether altered myelination of the UF may play a role in BD. Lastly, we investigate potential sources of heterogeneity in findings in the UF, such as age, sex ratio, percentage of individuals with BD taking lithium or anti-psychotic medication, percentage of individuals with BD with a lifetime comorbid anxiety disorder, and the diffusion tensor imaging processing pipeline.
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