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Description: Although the EQ-5D instruments have been initially designed to adult populations, there are new studies evaluating and applying these instruments in children and adolescents. The EuroQol Group adapted and created two versions designed for children and adolescents. The measurement properties of these instruments have been tested in different health conditions. The lack of a systematic review with recent data assessing the risk of bias of the studies and the lack of a systematic assessment of the newly EQ-5D-Y versions does not allow us to have a comprehensive evaluation of the validity, reliability and responsiveness of these instruments among children and adolescents. Thus, the aim of this systematic review is to critically appraise and summarize the evidence on the measurement properties of the EQ-5D instruments (self-reported version – answered by children and adolescents; and proxy versions – versions reported by parents, caregivers or health professionals) in children and adolescents.


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