This study aims to (a) identify the social-cognitive factors related to condom use, and the associated processes by which the factors affect behavior, in a cumulative synthesis of individual-level theories applied in this domain in sub-Saharan Africa; (b) identify key moderators of the association between theoretical antecedents and condom use; (c) synthesize the antecedents derived from the extant evidence in an integrated theoretical model, providing a comprehensive explanation of the antecedents of the study condom use in this population, and the associated processes by which the antecedents relate to behavior; (d) test the fit of a theoretically determined network of relationships among the constructs from the integrated model of model of condom use with data from theoretical research on young people in sub-Saharan Africa; (e) test the effect of methodological quality as a moderator of effects between social cognitive variables and condom use; and (f) highlight how the new integrated model will serve to inform future research and practice on condom use in this population. Consequently, this meta-analysis will make a unique contribution to the literature by synthesizing and critically apprising extant evidence for young peoples’ condom use in SSA - a critical behavior shown to limit the spread of HIV, a priority public health issue in the region.