Nanopore sequencing undergoes catastrophic sequence failure at inverted duplicated DNA sequences

,; Spealman, Pieter

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Nanopore sequencing undergoes catastrophic sequence failure at inverted duplicated DNA sequences

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Affiliated institutions: New York University

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Nanopore sequencing undergoes catastrophic sequence failure at inverted duplicated DNA sequences

Pieter Spealman, Jaden Burrell, and David Gresham

Inverted duplicated sequences are a common feature of structural variants (SVs) and copy number variants (CNVs). Analysis of CNVs containing inverted duplicated sequences using nanopore sequencing identified recurrent aberrant behavior charac…

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