The COV19Mx (COVID-19 National Data Registry of Mexico) is a prospective cohort that retrieves information from the Mexican National Registry of Coronavirus. It is updated daily with data from 475 monitoring hospitals of viral respiratory diseases located in the 32 states of Mexico. The respiratory infection monitoring units are part of the Mexican Public Health Network (MPHN). Included hospitals are part of the National Mexican Institute of Social Security (IMSS), The Institute of Security and Social Services for State Workers (ISSSTE), The Secretary of National Defense (SEDENA), The Secretary of the Navy of the Mexican Republic (SEMAR), and The National Health Department (SSA). These monitoring units are the only ones approved to perform RT-PCR analysis for SARS-CoV-2 in Mexico, and are the reference centers for COVID-19 suspected patients. Data of the National Cohort (last accessed on May 28th, 2020) is fully available at: https://datos.gob.mx/busca/dataset/informacion-referente-a-casos-covid-19-en-mexico/resource/e8c7079c-dc2a-4b6e-8035-08042ed37165?inner_span=True.