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Description: The increasing number of people born after assisted reproductive technology, in particular with in vitro fertilization (IVF), and interest in the developmental origins of health and disease, have led to concerns that conception through IVF could have adverse cardio-metabolic effects. Given that the first successful IVF treatments were completed 40 years ago, few IVF conceived people are old enough to have experienced cardiovascular events, but a small number of studies suggest that IVF might influence offspring cardio-metabolic risk factors in childhood. The primary aim of this work is to examine the effects of IVF (versus spontaneous conception) on offspring growth, adiposity and cardio-metabolic outcomes in a large sample of people from different birth cohorts.

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