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Open Science COVID-19 Management Using Bayesian Inference  /

COVID-19 Non-critical hospital-based management: Adaptive platform RCT for treatment of hospitalised patients with epidemic viral respiratory disease

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Description: This is an open science generic template design for a Bayesian adaptive platform RCT of therapy for hospitalised patients with acute viral respiratory disease. It will accommodate early stopping for success, retirement of futile interventions, and incorporation of new arms over time. It is freely available to be used by research or commercial sponsors with attribution.

License: CC-By Attribution 4.0 International

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Background: In early 2020 a global pandemic of COVID-19, a severe respiratory illness caused by infection with the SARS-CoV-2 virus, was declared by the World Health Organization. As an emergent pathogen, little is known about how best to manage it, and as of March 21st 2020 there were no known effective treatments. It is apparent that there is an urgent need to determine what works, what doesn't,...

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