Target of replication: *A priori* experimental protocols for the _in vivo_ portion of the replication, materials, and confirmatory analysis plans were peer reviewed, [pre-registered][1], and published by [*eLife*][2]. This component includes all data, analysis scripts, and methods for the replication of the experiment reported in Figure 7C-E of [Delmore et al., 2011][3]. This experiment assesses the effect of JQ1 treatment on tumor growth. [Figures component][4] contains a visualization of replication results. These figures are the same as can be found in the Replication Study and include Figure 2 displaying overall survival and Figure 3 displaying tumor burden. These scripts will call data directly from the OSF. [Statistical Analyses component][5] contains R scripts that were used for the analysis. These scripts will call data directly from the OSF. [Data component][6] contains data generated from the experimental work and files used in the analysis and generation of figures, which are in .csv format. [Methods component][7] contains methodology details for this replication attempt which are described in the [Registered Report][8]. [Cell line quality control data][9] includes results confirming the cells lines was free from mycoplasma contamination as well as STR DNA profiling of the cell lines used. [1]: https://osf.io/ng3st/ [2]: https://elifesciences.org/content/4/e07072 [3]: http://www.cell.com/cell/abstract/S0092-8674(11)00943-3?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867411009433%3Fshowall%3Dtrue [4]: https://osf.io/kf7ze/wiki/home/ [5]: https://osf.io/yznr4/wiki/home/ [6]: https://osf.io/jse9q/wiki/home/ [7]: https://osf.io/pbw39/wiki/home/ [8]: https://elifesciences.org/content/4/e07072 [9]: https://osf.io/r38p3/wiki/home/