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Replication Studies  /

Affiliated institutions: Center For Open Science

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Category: Project

Description: Replication of "Wnt activity defines colon cancer stem cells and is regulated by the microenvironment”. Includes information to prepare the replication experiments. Includes data, code, and digital materials from completed replication experiments.

License: CC-By Attribution 4.0 International

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Type: Individual replications
Status: Fully completed


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Replication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment


**Abstract:**

As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Evans et al., 2015), that described how we intended to replicate selected experiments from the paper "Wnt activity defines colon cancer stem cells and is regulated by the microenvironment" (

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Components

Clonogenicity assay of TOP-GFP CSC clones

Essex, Pineda, Evans & 5 more

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Tumorigenicity assay of TOP-GFP CSC clone

Essex, Pineda, Acharya & 7 more

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Meta Analysis


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Study 9: Registered Report Additional Materials

Evans, Essex, Xin & 8 more

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Tags

Cancer stem cellMetascienceReplicationReproducibilityReproducibility Project: Cancer BiologyWnt signaling pathway

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