Ventral hippocampus interacts with prelimbic cortex during inhibition of threat response via learned safety in both mice and humans

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  1. Francis Lee

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Description: Cross-species dataset for conditioned inhibition via safety signal learning tasks

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Heightened fear and inefficient safety learning are key features of fear and anxiety disorders. Evidence-based interventions for anxiety disorders, such as cognitive behavioral therapy, primarily rely on mechanisms of fear extinction. However, up to 50% of clinically anxious individuals do not respond to current evidence-based treatment, suggesting a critical need for new interventions based on al...

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