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Description: In the context of the COVID-19 pandemic, French public opinion has been divided about Pr. Didier Raoult and his hydroxychloroquine-based treatment against COVID-19. In this paper, our aim is to contribute to the understanding of this polarization of public opinion by investigating the relationship between (analytic vs. intuitive) cognitive style and trust in Didier Raoult and his treatment. Through three studies (total N after exclusion = 950), we found that a more intuitive cognitive style predicted higher trust in Didier Raoult and his treatment. Moreover, we found that Trust in Raoult was positively associated with belief that truth is political, belief in conspiracy theories, belief in pseudo-medicines and pseudo-medical and conspiratorial beliefs regarding the COVID-19 pandemic. We also found a negative association with knowledge of scientific methods and regard for scientific method over personal experience. However, higher trust in Didier Raoult was not associated with self-reported compliance with official regulations concerning the COVID-19 pandemic.