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**Trial registration** This trial is registered at the Trial registry Australian New Zealand Clinical Trials Registry: [ACTRN12613000901707][1] **Trial analysis** [Here you will find the most recent version of the analysis script][2]. ## How to use the OSF to manage a clinical research workflow ## 1. In this **Component**, store and share analysis plan information and analysis code. This is a great place to collaborate with a statistician, while also documenting the evolution of your study analysis. 2. Add your team to this component by using the **Contributors** tab at the top. a. Remember not to add blinded team members to a component that contains materials that might comprimise their blinded state. b. Provide team members with **Permissions** to reflect what control they need over the materials. Allocate Administrative permissions to only those who require them (eg, PIs) to avoid study information from being made public accidentally, which could violate blinding. Team members should have Read or Read + Write permissions. 3. Use the **Wiki** to provide instruction and direction to your team, such as how to find materials or how to use them properly. Updates to information in the **Wiki** allow documentation of the study as the content is tracked using **Verison Control**. 4. **Upload** your non-sensitive research materials into the appropriate **Component** of the project. When new versions of these materials are available, upload them again with the same filename. All these versions will remain available, but the most recent will be the one your team will navigate to when they select that file. This is because all changes to files on the OSF are tracked using **Verison Control**. 5. **Connect** your OSF project with other research services your team uses, such as Google Drive, Dropbox, Box, Dataverse, and many more. Select the **Settings** tab and pick your **Add-ons**. Do not connect to **Add-on** locations that also house materials that contain PHI to prevent accidental copying of sensitive material into OSF storage. [1]: https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=364758 [2]: https://osf.io/t6n5j/
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