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Description: Replication of "COT drives resistance to RAF inhibition through MAP kinase pathway reactivation”. Includes information to prepare the replication experiments. Includes data, code, and digital materials from partially completed replication experiments.
This project contains all information pertaining to the replication of experiments from “COT drives resistance to RAF inhibition through MAP kinase pathway reactivation” published in Nature in 2010 (Johannessen et al., 2010). Experimental work began although not all experiments were completed. The completed experiments were included in the summary paper "Experiments from unfinished Registered Repo…
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