Interpretation of scientific findings requires the reader to understand
what was being tested, how it was tested, how it was analyzed, and what
results were obtained. Scientific articles are the primary means to
communicate these pieces of information. However, what constitutes as
enough information is not always clear or known and varies by discipline,
journal, and scientist. Additionally, this varies over time as established
methodologies mature and new methodologies emerge. This presentation will
focus on the barriers encountered when gathering this information as part
of the Reproducibility Project: Cancer Biology (https://osf.io/
e81xl/wiki/home/), a project to assess reproducibility rates, predictors of
reproducibility, and common obstacles to conducting replications in
preclinical cancer biology. The replications illustrate some of the
challenges and opportunities in how research is conducted and communicated.
